There is a fundamental need to reform data-sharing governance practices to ensure their effectiveness and sustainability. We advance here a guidebook, each step of which is equipped with resources and case studies, to aid stakeholders and actors as they navigate the legal, technical, organizational, and societal challenges to creating good governance practices for responsible and impactful data-sharing collaboratives. This framework aims to provide a holistic guide that encourages data-sharing parties to consider technical, legal, as well as ethical components of sharing.